Nicotine Alters Estrogen Receptor-Beta-Regulated Inflammasome Activity and Exacerbates Ischemic Brain Damage in Female Rats

Smoking is a preventable risk factor for stroke and smoking-derived nicotine exacerbates post-ischemic damage via inhibition of estrogen receptor beta (ER-β) signaling in the brain of female rats. ER-β regulates inflammasome activation in the brain. Therefore, we hypothesized that chronic nicotine e...

Descripción completa

Detalles Bibliográficos
Autores principales: d’Adesky, Nathan D., de Rivero Vaccari, Juan Pablo, Bhattacharya, Pallab, Schatz, Marc, Perez-Pinzon, Miguel A., Bramlett, Helen M., Raval, Ami P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983576/
https://www.ncbi.nlm.nih.gov/pubmed/29710856
http://dx.doi.org/10.3390/ijms19051330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983576/
https://www.ncbi.nlm.nih.gov/pubmed/29710856
http://dx.doi.org/10.3390/ijms19051330

Ejemplares similares