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Nicotine Alters Estrogen Receptor-Beta-Regulated Inflammasome Activity and Exacerbates Ischemic Brain Damage in Female Rats

Smoking is a preventable risk factor for stroke and smoking-derived nicotine exacerbates post-ischemic damage via inhibition of estrogen receptor beta (ER-β) signaling in the brain of female rats. ER-β regulates inflammasome activation in the brain. Therefore, we hypothesized that chronic nicotine e...

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Detalles Bibliográficos
Autores principales:	d’Adesky, Nathan D., de Rivero Vaccari, Juan Pablo, Bhattacharya, Pallab, Schatz, Marc, Perez-Pinzon, Miguel A., Bramlett, Helen M., Raval, Ami P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983576/ https://www.ncbi.nlm.nih.gov/pubmed/29710856 http://dx.doi.org/10.3390/ijms19051330

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