Co-Administration of Melatonin Effectively Enhances the Therapeutic Effects of Pioglitazone on Mesenchymal Stem Cells Undergoing Indoxyl Sulfate-Induced Senescence through Modulation of Cellular Prion Protein Expression

Background: Mesenchymal stem cells (MSCs) are a promising source for regenerative medicine. However, their therapeutic potential in patients with chronic kidney disease (CKD) is restricted by the presence of uremic toxins. To address this limitation, we explored the protective effect of melatonin an...

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Detalles Bibliográficos
Autores principales: Han, Yong Seok, Kim, Sang Min, Lee, Jun Hee, Lee, Sang Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983612/
https://www.ncbi.nlm.nih.gov/pubmed/29734669
http://dx.doi.org/10.3390/ijms19051367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983612/
https://www.ncbi.nlm.nih.gov/pubmed/29734669
http://dx.doi.org/10.3390/ijms19051367

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