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Inhibition of Arachidonate 12/15-Lipoxygenase Improves α-Galactosidase Efficacy in iPSC-Derived Cardiomyocytes from Fabry Patients

(1) Background: A high incidence of intervening sequence (IVS)4+919 G>A mutation with later-onset cardiac phenotype have been reported in a majority of Taiwan Fabry cohorts. Some evidence indicated that conventional biomarkers failed to predict the long-term progression and therapeutic outcome; (...

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Detalles Bibliográficos
Autores principales: Chien, Yueh, Chou, Shih-Jie, Chang, Yuh-Lih, Leu, Hsin-Bang, Yang, Yi-Ping, Tsai, Ping-Hsing, Lai, Ying-Hsiu, Chen, Kuan-Hsuan, Chang, Wei-Chao, Sung, Shih-Hsien, Yu, Wen-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983630/
https://www.ncbi.nlm.nih.gov/pubmed/29772700
http://dx.doi.org/10.3390/ijms19051480