Cargando…
Why Two? On the Role of (A-)Symmetry in Negative Supercoiling of DNA by Gyrase
Gyrase is a type IIA topoisomerase that catalyzes negative supercoiling of DNA. The enzyme consists of two GyrA and two GyrB subunits. It is believed to introduce negative supercoils into DNA by converting a positive DNA node into a negative node through strand passage: First, it cleaves both DNA st...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983639/ https://www.ncbi.nlm.nih.gov/pubmed/29772727 http://dx.doi.org/10.3390/ijms19051489 |