Autophagic Regulation of p62 is Critical for Cancer Therapy

Sequestosome1 (p62/SQSTM 1) is a multidomain protein that interacts with the autophagy machinery as a key adaptor of target cargo. It interacts with phagophores through the LC3-interacting (LIR) domain and with the ubiquitinated protein aggregates through the ubiquitin-associated domain (UBA) domain...

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Detalles Bibliográficos
Autores principales: Islam, Md. Ariful, Sooro, Mopa Alina, Zhang, Pinghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983640/
https://www.ncbi.nlm.nih.gov/pubmed/29738493
http://dx.doi.org/10.3390/ijms19051405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983640/
https://www.ncbi.nlm.nih.gov/pubmed/29738493
http://dx.doi.org/10.3390/ijms19051405

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