Application of 3D-QSAR, Pharmacophore, and Molecular Docking in the Molecular Design of Diarylpyrimidine Derivatives as HIV-1 Nonnucleoside Reverse Transcriptase Inhibitors

Diarylpyrimidines (DAPYs), acting as HIV-1 nonnucleoside reverse transcriptase inhibitors (NNRTIs), have been considered to be one of the most potent drug families in the fight against acquired immunodeficiency syndrome (AIDS). To better understand the structural requirements of HIV-1 NNRTIs, three-...

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Detalles Bibliográficos
Autores principales: Liu, Genyan, Wang, Wenjie, Wan, Youlan, Ju, Xiulian, Gu, Shuangxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983643/
https://www.ncbi.nlm.nih.gov/pubmed/29751616
http://dx.doi.org/10.3390/ijms19051436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983643/
https://www.ncbi.nlm.nih.gov/pubmed/29751616
http://dx.doi.org/10.3390/ijms19051436

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