Insights into the Origin of Distinct Medin Fibril Morphologies Induced by Incubation Conditions and Seeding

Incubation conditions are an important factor to consider when studying protein aggregation in vitro. Here, we employed biophysical methods and atomic force microscopy to show that agitation dramatically alters the morphology of medin, an amyloid protein deposited in the aorta. Agitation reduces the...

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Detalles Bibliográficos
Autores principales: Davies, Hannah A., Lee, Chiu Fan, Miller, Leanne, Liu, Lu-Ning, Madine, Jillian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983645/
https://www.ncbi.nlm.nih.gov/pubmed/29751581
http://dx.doi.org/10.3390/ijms19051357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983645/
https://www.ncbi.nlm.nih.gov/pubmed/29751581
http://dx.doi.org/10.3390/ijms19051357

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