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Insights into the Origin of Distinct Medin Fibril Morphologies Induced by Incubation Conditions and Seeding
Incubation conditions are an important factor to consider when studying protein aggregation in vitro. Here, we employed biophysical methods and atomic force microscopy to show that agitation dramatically alters the morphology of medin, an amyloid protein deposited in the aorta. Agitation reduces the...
Autores principales: | Davies, Hannah A., Lee, Chiu Fan, Miller, Leanne, Liu, Lu-Ning, Madine, Jillian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983645/ https://www.ncbi.nlm.nih.gov/pubmed/29751581 http://dx.doi.org/10.3390/ijms19051357 |
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