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A Combined NMR-Computational Study of the Interaction between Influenza Virus Hemagglutinin and Sialic Derivatives from Human and Avian Receptors on the Surface of Transfected Cells

The development of small-molecule inhibitors of influenza virus Hemagglutinin could be relevant to the opposition of the diffusion of new pandemic viruses. In this work, we made use of Nuclear Magnetic Resonance (NMR) spectroscopy to study the interaction between two derivatives of sialic acid, Neu5...

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Detalles Bibliográficos
Autores principales: Vasile, Francesca, Panigada, Maddalena, Siccardi, Antonio, Potenza, Donatella, Tiana, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983646/
https://www.ncbi.nlm.nih.gov/pubmed/29695047
http://dx.doi.org/10.3390/ijms19051267