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The Effect of Bornyl cis-4-Hydroxycinnamate on Melanoma Cell Apoptosis Is Associated with Mitochondrial Dysfunction and Endoplasmic Reticulum Stress

Bornyl cis-4-hydroxycinnamate, an active compound isolated from Piper betle stems, was investigated in terms of its effects on A2058 and A375 melanoma cell proliferation and protein expression in this study. We used flow cytometric analysis to examine the early stages of apoptosis induced by bornyl...

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Detalles Bibliográficos
Autores principales: Yang, Tzu-Yen, Wu, Yu-Jen, Chang, Chi-I, Chiu, Chien-Chih, Wu, Mei-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983650/
https://www.ncbi.nlm.nih.gov/pubmed/29734677
http://dx.doi.org/10.3390/ijms19051370