ScFvs as Allosteric Inhibitors of VEGFR-2: Novel Tools to Harness VEGF Signaling

Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2) is the main mediator of angiogenic signaling in endothelial cells and a primary responder to VEGF. VEGF dependent VEGFR-2 activation regulates endothelial cell migration and proliferation, as well as vessel permeability. VEGF is presented as an...

Descripción completa

Detalles Bibliográficos
Autores principales: Ballmer-Hofer, Kurt, A.C. Hyde, Caroline, Schleier, Thomas, Avramovic, Dragana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983656/
https://www.ncbi.nlm.nih.gov/pubmed/29723982
http://dx.doi.org/10.3390/ijms19051334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983656/
https://www.ncbi.nlm.nih.gov/pubmed/29723982
http://dx.doi.org/10.3390/ijms19051334

Ejemplares similares