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ScFvs as Allosteric Inhibitors of VEGFR-2: Novel Tools to Harness VEGF Signaling

Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2) is the main mediator of angiogenic signaling in endothelial cells and a primary responder to VEGF. VEGF dependent VEGFR-2 activation regulates endothelial cell migration and proliferation, as well as vessel permeability. VEGF is presented as an...

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Detalles Bibliográficos
Autores principales:	Ballmer-Hofer, Kurt, A.C. Hyde, Caroline, Schleier, Thomas, Avramovic, Dragana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983656/ https://www.ncbi.nlm.nih.gov/pubmed/29723982 http://dx.doi.org/10.3390/ijms19051334

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