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cPKCγ-Modulated Sequential Reactivation of mTOR Inhibited Autophagic Flux in Neurons Exposed to Oxygen Glucose Deprivation/Reperfusion

We have reported that conventional protein kinase Cγ (cPKCγ)-modulated neuron-specific autophagy improved the neurological outcome of mice following ischemic stroke through the Akt-mechanistic target of rapamycin (mTOR) pathway. However, its detailed molecular mechanism remains unclear. In this stud...

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Detalles Bibliográficos
Autores principales: Hua, Rongrong, Han, Song, Zhang, Nan, Dai, Qingqing, Liu, Ting, Li, Junfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983661/
https://www.ncbi.nlm.nih.gov/pubmed/29734780
http://dx.doi.org/10.3390/ijms19051380