Targeting Splicing in Prostate Cancer

Over 95% of human genes are alternatively spliced, expressing splice isoforms that often exhibit antagonistic functions. We describe genes whose alternative splicing has been linked to prostate cancer; namely VEGFA, KLF6, BCL2L2, ERG, and AR. We discuss opportunities to develop novel therapies that...

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Detalles Bibliográficos
Autores principales: Antonopoulou, Effrosyni, Ladomery, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983716/
https://www.ncbi.nlm.nih.gov/pubmed/29693622
http://dx.doi.org/10.3390/ijms19051287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983716/
https://www.ncbi.nlm.nih.gov/pubmed/29693622
http://dx.doi.org/10.3390/ijms19051287

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