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Targeting Splicing in Prostate Cancer

Over 95% of human genes are alternatively spliced, expressing splice isoforms that often exhibit antagonistic functions. We describe genes whose alternative splicing has been linked to prostate cancer; namely VEGFA, KLF6, BCL2L2, ERG, and AR. We discuss opportunities to develop novel therapies that...

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Detalles Bibliográficos
Autores principales:	Antonopoulou, Effrosyni, Ladomery, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983716/ https://www.ncbi.nlm.nih.gov/pubmed/29693622 http://dx.doi.org/10.3390/ijms19051287

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