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mTOR Signaling and Neural Stem Cells: The Tuberous Sclerosis Complex Model

The mechanistic target of rapamycin (mTOR), a serine-threonine kinase, plays a pivotal role in regulating cell growth and proliferation. Notably, a great deal of evidence indicates that mTOR signaling is also crucial in controlling proliferation and differentiation of several stem cell compartments....

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Detalles Bibliográficos
Autores principales: Polchi, Alice, Magini, Alessandro, Meo, Danila Di, Tancini, Brunella, Emiliani, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983755/
https://www.ncbi.nlm.nih.gov/pubmed/29772672
http://dx.doi.org/10.3390/ijms19051474