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mTOR Signaling and Neural Stem Cells: The Tuberous Sclerosis Complex Model
The mechanistic target of rapamycin (mTOR), a serine-threonine kinase, plays a pivotal role in regulating cell growth and proliferation. Notably, a great deal of evidence indicates that mTOR signaling is also crucial in controlling proliferation and differentiation of several stem cell compartments....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983755/ https://www.ncbi.nlm.nih.gov/pubmed/29772672 http://dx.doi.org/10.3390/ijms19051474 |