GDF11 Modulates Ca(2+)-Dependent Smad2/3 Signaling to Prevent Cardiomyocyte Hypertrophy

Growth differentiation factor 11 (GDF11), a member of the transforming growth factor-β family, has been shown to act as a negative regulator in cardiac hypertrophy. Ca(2+) signaling modulates cardiomyocyte growth; however, the role of Ca(2+)-dependent mechanisms in mediating the effects of GDF11 rem...

Descripción completa

Detalles Bibliográficos
Autores principales: Duran, Javier, Troncoso, Mayarling Francisca, Lagos, Daniel, Ramos, Sebastian, Marin, Gabriel, Estrada, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983757/
https://www.ncbi.nlm.nih.gov/pubmed/29783655
http://dx.doi.org/10.3390/ijms19051508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983757/
https://www.ncbi.nlm.nih.gov/pubmed/29783655
http://dx.doi.org/10.3390/ijms19051508

Ejemplares similares