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GDF11 Modulates Ca(2+)-Dependent Smad2/3 Signaling to Prevent Cardiomyocyte Hypertrophy

Growth differentiation factor 11 (GDF11), a member of the transforming growth factor-β family, has been shown to act as a negative regulator in cardiac hypertrophy. Ca(2+) signaling modulates cardiomyocyte growth; however, the role of Ca(2+)-dependent mechanisms in mediating the effects of GDF11 rem...

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Detalles Bibliográficos
Autores principales:	Duran, Javier, Troncoso, Mayarling Francisca, Lagos, Daniel, Ramos, Sebastian, Marin, Gabriel, Estrada, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983757/ https://www.ncbi.nlm.nih.gov/pubmed/29783655 http://dx.doi.org/10.3390/ijms19051508

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