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Incorporation of Synthetic mRNA in Injectable Chitosan-Alginate Hybrid Hydrogels for Local and Sustained Expression of Exogenous Proteins in Cells

The application of synthetic messenger RNA (mRNA) exhibits various advantages, such as expression of desired proteins in cells without genomic integration. In the field of tissue engineering, synthetic mRNAs could be also used to modulate the protein expression in implanted cells. Therefore, in this...

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Detalles Bibliográficos
Autores principales: Steinle, Heidrun, Ionescu, Tudor-Mihai, Schenk, Selina, Golombek, Sonia, Kunnakattu, Silju-John, Tutku Özbek, Melek, Schlensak, Christian, Wendel, Hans Peter, Avci-Adali, Meltem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983784/
https://www.ncbi.nlm.nih.gov/pubmed/29702615
http://dx.doi.org/10.3390/ijms19051313