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S-phase Synchronization Facilitates the Early Progression of Induced-Cardiomyocyte Reprogramming through Enhanced Cell-Cycle Exit

Direct reprogramming of fibroblasts into induced cardiomyocytes (iCMs) holds a great promise for regenerative medicine and has been studied in several major directions. However, cell-cycle regulation, a fundamental biological process, has not been investigated during iCM-reprogramming. Here, our tim...

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Detalles Bibliográficos
Autores principales: Bektik, Emre, Dennis, Adrienne, Pawlowski, Gary, Zhou, Chen, Maleski, Danielle, Takahashi, Satoru, Laurita, Kenneth R., Deschênes, Isabelle, Fu, Ji-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983785/
https://www.ncbi.nlm.nih.gov/pubmed/29734659
http://dx.doi.org/10.3390/ijms19051364