Deleterious Effect of Advanced CKD on Glyoxalase System Activity not Limited to Diabetes Aetiology

Methylglyoxal production is increased in diabetes. Methylglyoxal is efficiently detoxified by enzyme glyoxalase 1 (GLO1). The aim was to study the effect of diabetic and CKD milieu on (a) GLO1 gene expression in peripheral blood mononuclear cells; (b) GLO1 protein levels in whole blood; and (c) GLO1...

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Detalles Bibliográficos
Autores principales: Pácal, Lukáš, Chalásová, Katarína, Pleskačová, Anna, Řehořová, Jitka, Tomandl, Josef, Kaňková, Kateřina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983829/
https://www.ncbi.nlm.nih.gov/pubmed/29783710
http://dx.doi.org/10.3390/ijms19051517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983829/
https://www.ncbi.nlm.nih.gov/pubmed/29783710
http://dx.doi.org/10.3390/ijms19051517

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