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Metabolic Reprogramming by 3-Iodothyronamine (T1AM): A New Perspective to Reverse Obesity through Co-Regulation of Sirtuin 4 and 6 Expression

Obesity is a complex disease associated with environmental and genetic factors. 3-Iodothyronamine (T1AM) has revealed great potential as an effective weight loss drug. We used metabolomics and associated transcriptional gene and protein expression analysis to investigate the tissue specific metaboli...

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Detalles Bibliográficos
Autores principales: Assadi-Porter, Fariba M., Reiland, Hannah, Sabatini, Martina, Lorenzini, Leonardo, Carnicelli, Vittoria, Rogowski, Micheal, Selen Alpergin, Ebru S., Tonelli, Marco, Ghelardoni, Sandra, Saba, Alessandro, Zucchi, Riccardo, Chiellini, Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983833/
https://www.ncbi.nlm.nih.gov/pubmed/29786646
http://dx.doi.org/10.3390/ijms19051535