S1P(4) Regulates Passive Systemic Anaphylaxis in Mice but Is Dispensable for Canonical IgE-Mediated Responses in Mast Cells

Mast cells are key players in the development of inflammatory allergic reactions. Cross-linking of the high-affinity receptor for IgE (FcεRI) on mast cells leads to the generation and secretion of the sphingolipid mediator, sphingosine-1-phosphate (S1P) which is able, in turn, to transactivate its r...

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Detalles Bibliográficos
Autores principales: Kulinski, Joseph M., Proia, Richard L., Larson, Elisabeth M., Metcalfe, Dean D., Olivera, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983835/
https://www.ncbi.nlm.nih.gov/pubmed/29693558
http://dx.doi.org/10.3390/ijms19051279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983835/
https://www.ncbi.nlm.nih.gov/pubmed/29693558
http://dx.doi.org/10.3390/ijms19051279

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