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Multiple roles of core protein linker in hepatitis B virus replication

Hepatitis B virus (HBV) core protein (HBc) contains an N-terminal domain (NTD, assembly domain) and a C-terminal domain (CTD), which are linked by a flexible linker region. HBc plays multiple essential roles in viral replication, including capsid assembly, packaging of the viral pregenomic RNA (pgRN...

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Detalles Bibliográficos
Autores principales: Liu, Kuancheng, Luckenbaugh, Laurie, Ning, Xiaojun, Xi, Ji, Hu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983865/
https://www.ncbi.nlm.nih.gov/pubmed/29782550
http://dx.doi.org/10.1371/journal.ppat.1007085