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Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein

RNA viruses induce specialized membranous structures for use in genome replication. These structures are often referred to as replication organelles (ROs). ROs exhibit distinct lipid composition relative to other cellular membranes. In many picornaviruses, phosphatidylinositol-4-phosphate (PI4P) is...

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Detalles Bibliográficos
Autores principales: Banerjee, Sravani, Aponte-Diaz, David, Yeager, Calvin, Sharma, Suresh D., Ning, Gang, Oh, Hyung S., Han, Qingxia, Umeda, Masato, Hara, Yuji, Wang, Robert Y. L., Cameron, Craig E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983871/
https://www.ncbi.nlm.nih.gov/pubmed/29782554
http://dx.doi.org/10.1371/journal.ppat.1007086