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Evaluation and application of summary statistic imputation to discover new height-associated loci
As most of the heritability of complex traits is attributed to common and low frequency genetic variants, imputing them by combining genotyping chips and large sequenced reference panels is the most cost-effective approach to discover the genetic basis of these traits. Association summary statistics...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983877/ https://www.ncbi.nlm.nih.gov/pubmed/29782485 http://dx.doi.org/10.1371/journal.pgen.1007371 |