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Translational control of the undifferentiated phenotype in ER-positive breast tumor cells: Cytoplasmic localization of ERα and impact of IRES inhibition

Using a series of potential biomarkers relevant to mechanisms of protein synthesis, we observed that estrogen receptor (ER)-positive breast tumor cells exist in two distinct yet interconvertible phenotypic states (of roughly equal proportion) which differ in the degree of differentiation and use of...

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Detalles Bibliográficos
Autores principales: Vaklavas, Christos, Zinn, Kurt R., Samuel, Sharon L., Meng, Zheng, Grizzle, William E., Choi, Hyoungsoo, Blume, Scott W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983923/
https://www.ncbi.nlm.nih.gov/pubmed/29620220
http://dx.doi.org/10.3892/or.2018.6332