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Loss of RUNX3 is significantly associated with advanced tumor grade and stage in endometrial cancers

Loss of runt-related transcription factor 3 (RUNX3) has been reported in various cancers, and one of the mechanisms mediating loss of RUNX3 expression is DNA methylation. However, the role of RUNX3 expression and its DNA methylation status as prognostic factors in endometrial cancer remain unclear....

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Detalles Bibliográficos
Autores principales: Jeong, Dongjun, Kim, Hyungjoo, Ryu, Aeli, Sunwoo, Jaegun, Choi, Seung Do, Nam, Gye Hyun, Jeon, Seob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983989/
https://www.ncbi.nlm.nih.gov/pubmed/29693143
http://dx.doi.org/10.3892/mmr.2018.8915