The cJUN NH(2)-terminal kinase (JNK) signaling pathway promotes genome stability and prevents tumor initiation

Breast cancer is the most commonly diagnosed malignancy in women. Analysis of breast cancer genomic DNA indicates frequent loss-of-function mutations in components of the cJUN NH(2)-terminal kinase (JNK) signaling pathway. Since JNK signaling can promote cell proliferation by activating the AP1 tran...

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Detalles Bibliográficos
Autores principales: Girnius, Nomeda, Edwards, Yvonne JK, Garlick, David S, Davis, Roger J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984035/
https://www.ncbi.nlm.nih.gov/pubmed/29856313
http://dx.doi.org/10.7554/eLife.36389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984035/
https://www.ncbi.nlm.nih.gov/pubmed/29856313
http://dx.doi.org/10.7554/eLife.36389

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