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Improvement of Cell Cycle Lifespan and Genetic Damage Susceptibility of Human Mesenchymal Stem Cells by Hypoxic Priming

Hypoxic culture is widely recognized as a method to efficiently expand human mesenchymal stem cells (MSCs) without loss of stem cell properties. However, the molecular basis of how hypoxia priming benefits MSC expansion remains unclear. We report that hypoxic priming markedly extends the cell cycle...

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Detalles Bibliográficos
Autores principales: Lee, Chang-Woo, Kang, Dongrim, Kim, Ae-Kyeong, Kim, Dong-Young, Kim, Dong-Ik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984059/
https://www.ncbi.nlm.nih.gov/pubmed/29699381
http://dx.doi.org/10.15283/ijsc17054