The Bromodomain Inhibitor JQ1 Enhances the Responses to All-trans Retinoic Acid in HL-60 and MV4-11 Leukemia Cells

All-trans retinoic acid (ATRA) is a highly effective treatment for acute promyelocytic leukemia (APL), a cytogenetically distinct subtype of acute myeloid leukemia (AML). However, ATRA-based treatment is not effective in other subtypes of AML. In non-APL AML, ATRA signaling pathway is impaired or do...

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Detalles Bibliográficos
Autores principales: Kang, Changhee, Kim, C-Yoon, Kim, Hyuk Soon, Park, Se-Pill, Chung, Hyung-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984067/
https://www.ncbi.nlm.nih.gov/pubmed/29699387
http://dx.doi.org/10.15283/ijsc18021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984067/
https://www.ncbi.nlm.nih.gov/pubmed/29699387
http://dx.doi.org/10.15283/ijsc18021

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