FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system

Disrupted in schizophrenia 1 (DISC1) is a multi-functional scaffolding protein that has been associated with neuropsychiatric disease. The role of DISC1 is to assemble protein complexes that promote neural development and signaling, hence tight control of the concentration of cellular DISC1 in neuro...

Descripción completa

Detalles Bibliográficos
Autores principales: Yalla, K, Elliott, C, Day, J P, Findlay, J, Barratt, S, Hughes, Z A, Wilson, L, Whiteley, E, Popiolek, M, Li, Y, Dunlop, J, Killick, R, Adams, D R, Brandon, N J, Houslay, M D, Hao, B, Baillie, G S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984089/
https://www.ncbi.nlm.nih.gov/pubmed/28727686
http://dx.doi.org/10.1038/mp.2017.138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984089/
https://www.ncbi.nlm.nih.gov/pubmed/28727686
http://dx.doi.org/10.1038/mp.2017.138

Ejemplares similares