Cargando…

FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system

Disrupted in schizophrenia 1 (DISC1) is a multi-functional scaffolding protein that has been associated with neuropsychiatric disease. The role of DISC1 is to assemble protein complexes that promote neural development and signaling, hence tight control of the concentration of cellular DISC1 in neuro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yalla, K, Elliott, C, Day, J P, Findlay, J, Barratt, S, Hughes, Z A, Wilson, L, Whiteley, E, Popiolek, M, Li, Y, Dunlop, J, Killick, R, Adams, D R, Brandon, N J, Houslay, M D, Hao, B, Baillie, G S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984089/ https://www.ncbi.nlm.nih.gov/pubmed/28727686 http://dx.doi.org/10.1038/mp.2017.138

Ejemplares similares

Ubiquitin-independent proteosomal degradation of myelin basic protein contributes to development of neurodegenerative autoimmunity
por: Belogurov, Alexey, et al.
Publicado: (2015)

Intersections of Ubiquitin-Proteosome System and Autophagy in Promoting Growth of Glioblastoma Multiforme: Challenges and Opportunities
por: Visintin, Rhett, et al.
Publicado: (2022)

Chemical informatics uncovers a new role for moexipril as a novel inhibitor of cAMP phosphodiesterase-4 (PDE4)
por: Cameron, Ryan T., et al.
Publicado: (2013)

Disruption of pro-oxidant and antioxidant systems with elevated expression of the ubiquitin proteosome system in the cachectic heart muscle of nude mice
por: Hinch, E. C. A., et al.
Publicado: (2013)

Kinectin1 depletion promotes EGFR degradation via the ubiquitin-proteosome system in cutaneous squamous cell carcinoma
por: Ma, Ji, et al.
Publicado: (2021)

Dimerization of cAMP phosphodiesterase-4 (PDE4) in living cells requires interfaces located in both the UCR1 and catalytic unit domains
por: Bolger, Graeme B., et al.
Publicado: (2015)

Raw Inonotus obliquus polysaccharide counteracts Alzheimer’s disease in a transgenic mouse model by activating the ubiquitin-proteosome system
por: Wang, Shumin, et al.
Publicado: (2023)

In search of the optimal proteosome inhibitor. How, when and for whom?
por: Engelhardt, Monika, et al.
Publicado: (2021)

Severe acute respiratory syndrome coronavirus protein 6 mediates ubiquitin-dependent proteosomal degradation of N-Myc (and STAT) interactor
por: Cheng, Weijia, et al.
Publicado: (2015)

LZTFL1 inhibits kidney tumor cell growth by destabilizing AKT through ZNRF1-mediated ubiquitin proteosome pathway
por: Lu, Jun, et al.
Publicado: (2023)

MTOR signaling and ubiquitin-proteosome gene expression in the preservation of fat free mass following high protein, calorie restricted weight loss
por: McIver, Cassandra M, et al.
Publicado: (2012)

Retracted: Phosphorylation of PDE4A5 by MAPKAPK2 attenuates fibrin degradation via p75 signalling
por: Houslay, K F, et al.
Publicado: (2019)

FBXW7 E3 ubiquitin ligase: degrading, not degrading, or being degraded
por: Lan, Huiyin, et al.
Publicado: (2019)

Both Ubiquitin Ligases FBXW8 and PARK2 Are Sequestrated into Insolubility by ATXN2 PolyQ Expansions, but Only FBXW8 Expression Is Dysregulated
por: Halbach, Melanie Vanessa, et al.
Publicado: (2015)

Proteosomal degradation of NSD2 by BRCA1 promotes leukemia cell differentiation
por: Park, Jin Woo, et al.
Publicado: (2020)

Proteosomal Degradation Impairs Transcytosis of AAV vectors from Suprachoroidal Space to Retina
por: Ding, Kun, et al.
Publicado: (2021)

Overexpression of microRNA-223 regulates the ubiquitin ligase FBXW7 in oesophageal squamous cell carcinoma
por: Kurashige, J, et al.
Publicado: (2012)

FBXW24 controls female meiotic prophase progression by regulating SYCP3 ubiquitination
por: Wang, Yang, et al.
Publicado: (2022)

Novel compound C150 inhibits pancreatic cancer through induction of ER stress and proteosome assembly
por: Wang, Tao, et al.
Publicado: (2022)

RAB40C regulates RACK1 stability via the ubiquitin–proteasome system
por: Day, Jon P, et al.
Publicado: (2018)

Identification of a multifunctional docking site on the catalytic unit of phosphodiesterase-4 (PDE4) that is utilised by multiple interaction partners
por: Houslay, Kirsty F., et al.
Publicado: (2017)

Peptides bound to proteosomes via hydrophobic feet become highly immunogenic without adjuvants
Publicado: (1988)

Enrichment of Autophagy and Proteosome Pathways in Breast Muscle of Feed Efficient Pedigree Male Broilers
por: Piekarski-Welsher, Alissa, et al.
Publicado: (2018)

Dysfunction of microRNA-32 regulates ubiquitin ligase FBXW7 in multiple myeloma disease
por: Hua, Jingsheng, et al.
Publicado: (2016)

An OBSL1-Cul7(Fbxw8) Ubiquitin Ligase Signaling Mechanism Regulates Golgi Morphology and Dendrite Patterning
por: Litterman, Nadia, et al.
Publicado: (2011)

The role of proteosome-mediated proteolysis in modulating potentially harmful transcription factor activity in Saccharomyces cerevisiae
por: Bonzanni, Nicola, et al.
Publicado: (2011)

GSK3β-SCF(FBXW7α) mediated phosphorylation and ubiquitination of IRF1 are required for its transcription-dependent turnover
por: Garvin, Alexander J, et al.
Publicado: (2019)

Loss of CDC4/FBXW7 in Gastric Carinoma
por: Milne, A. N., et al.
Publicado: (2010)

Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia
por: Zhu, Ting, et al.
Publicado: (2021)

CDK1/FBXW7 facilitates degradation and ubiquitination of MLST8 to inhibit progression of renal cell carcinoma
por: Zhang, Encheng, et al.
Publicado: (2021)

Nitric oxide-independent vasodilator rescues heme-oxidized soluble guanylate cyclase from proteosomal degradation
por: Meurer, Sabine, et al.
Publicado: (2009)

Trehalose Reverses Cell Malfunction in Fibroblasts from Normal and Huntington's Disease Patients Caused by Proteosome Inhibition
por: Fernandez-Estevez, Maria Angeles, et al.
Publicado: (2014)

Cholesterol Depletion in Adipocytes Causes Caveolae Collapse Concomitant with Proteosomal Degradation of Cavin-2 in a Switch-Like Fashion
por: Breen, Michael R., et al.
Publicado: (2012)

Disrupted-in-Schizophrenia-1 (DISC1) regulates spines of the glutamate synapse via Rac1
por: Hayashi-Takagi, Akiko, et al.
Publicado: (2010)

Intranasal immunization with a proteosome-adjuvanted SARS-CoV-2 spike protein-based vaccine is immunogenic and efficacious in mice and hamsters
por: Stark, Felicity C., et al.
Publicado: (2022)

Fbxw7 Controls Angiogenesis by Regulating Endothelial Notch Activity
por: Izumi, Nanae, et al.
Publicado: (2012)

Regulation of SOX10 stability via ubiquitination-mediated degradation by Fbxw7α modulates melanoma cell migration
por: Lv, Xiao-Bin, et al.
Publicado: (2015)

The anti‐angiogenesis role of FBXW7 in diabetic retinopathy by facilitating the ubiquitination degradation of c‐Myc to orchestrate the HDAC2
por: Hu, Lihua, et al.
Publicado: (2020)

The FBXW7‐NOTCH interactome: A ubiquitin proteasomal system‐induced crosstalk modulating oncogenic transformation in human tissues
por: Kar, Rohan, et al.
Publicado: (2021)

The E3 ubiquitin ligase, FBXW5, promotes the migration and invasion of gastric cancer through the dysregulation of the Hippo pathway
por: Yao, Yangyang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hs6q57dq929koo3pukb2fasa3l