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A simplified protocol for differentiation of electrophysiologically mature neuronal networks from human induced pluripotent stem cells

Progress in elucidating the molecular and cellular pathophysiology of neuropsychiatric disorders has been hindered by the limited availability of living human brain tissue. The emergence of induced pluripotent stem cells (iPSCs) has offered a unique alternative strategy using patient-derived functio...

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Detalles Bibliográficos
Autores principales: Gunhanlar, N, Shpak, G, van der Kroeg, M, Gouty-Colomer, L A, Munshi, S T, Lendemeijer, B, Ghazvini, M, Dupont, C, Hoogendijk, W J G, Gribnau, J, de Vrij, F M S, Kushner, S A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984104/
https://www.ncbi.nlm.nih.gov/pubmed/28416807
http://dx.doi.org/10.1038/mp.2017.56