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A simplified protocol for differentiation of electrophysiologically mature neuronal networks from human induced pluripotent stem cells
Progress in elucidating the molecular and cellular pathophysiology of neuropsychiatric disorders has been hindered by the limited availability of living human brain tissue. The emergence of induced pluripotent stem cells (iPSCs) has offered a unique alternative strategy using patient-derived functio...
Autores principales: | Gunhanlar, N, Shpak, G, van der Kroeg, M, Gouty-Colomer, L A, Munshi, S T, Lendemeijer, B, Ghazvini, M, Dupont, C, Hoogendijk, W J G, Gribnau, J, de Vrij, F M S, Kushner, S A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984104/ https://www.ncbi.nlm.nih.gov/pubmed/28416807 http://dx.doi.org/10.1038/mp.2017.56 |
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