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Treating hematological malignancies with drugs inhibiting ribosome biogenesis: when and why

It is well known that chemotherapy can cure only some cancers in advanced stage, mostly those with an intact p53 pathway. Hematological cancers such as lymphoma and certain forms of leukemia are paradigmatic examples of such scenario. Recent evidence indicates that the efficacy of many of the alkyla...

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Detalles Bibliográficos
Autores principales: Derenzini, Enrico, Rossi, Alessandra, Treré, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984324/
https://www.ncbi.nlm.nih.gov/pubmed/29855342
http://dx.doi.org/10.1186/s13045-018-0609-1