Cargando…
Module and individual domain deletions of NRPS to produce plipastatin derivatives in Bacillus subtilis
BACKGROUND: Plipastatin, an antifungal lipopeptide, is synthesized by a non-ribosomal peptide synthetase (NRPS) in Bacillus subtilis. However, little information is available on the combinatorial biosynthesis strategies applied in plipastatin biosynthetic pathway. In this study, we applied module or...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984369/ https://www.ncbi.nlm.nih.gov/pubmed/29855381 http://dx.doi.org/10.1186/s12934-018-0929-4 |