UMI-count modeling and differential expression analysis for single-cell RNA sequencing

Read counting and unique molecular identifier (UMI) counting are the principal gene expression quantification schemes used in single-cell RNA-sequencing (scRNA-seq) analysis. By using multiple scRNA-seq datasets, we reveal distinct distribution differences between these schemes and conclude that the...

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Detalles Bibliográficos
Autores principales: Chen, Wenan, Li, Yan, Easton, John, Finkelstein, David, Wu, Gang, Chen, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984373/
https://www.ncbi.nlm.nih.gov/pubmed/29855333
http://dx.doi.org/10.1186/s13059-018-1438-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984373/
https://www.ncbi.nlm.nih.gov/pubmed/29855333
http://dx.doi.org/10.1186/s13059-018-1438-9

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