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Connecting genetics and gene expression data for target prioritisation and drug repositioning
Developing new drugs continues to be a highly inefficient and costly business. By repurposing an existing compound for a different indication, drug repositioning offers an attractive alternative to traditional drug discovery. Most of these approaches work by matching transcriptional disease signatur...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984374/ https://www.ncbi.nlm.nih.gov/pubmed/29881461 http://dx.doi.org/10.1186/s13040-018-0171-y |