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Ythdf2-mediated m(6)A mRNA clearance modulates neural development in mice

BACKGROUND: N(6)-methyladenosine (m(6)A) modification in mRNAs was recently shown to be dynamically regulated, indicating a pivotal role in multiple developmental processes. Most recently, it was shown that the Mettl3-Mettl14 writer complex of this mark is required for the temporal control of cortic...

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Detalles Bibliográficos
Autores principales: Li, Miaomiao, Zhao, Xu, Wang, Wei, Shi, Hailing, Pan, Qingfei, Lu, Zhike, Perez, Sonia Peña, Suganthan, Rajikala, He, Chuan, Bjørås, Magnar, Klungland, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984442/
https://www.ncbi.nlm.nih.gov/pubmed/29855337
http://dx.doi.org/10.1186/s13059-018-1436-y