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Ythdf2-mediated m(6)A mRNA clearance modulates neural development in mice
BACKGROUND: N(6)-methyladenosine (m(6)A) modification in mRNAs was recently shown to be dynamically regulated, indicating a pivotal role in multiple developmental processes. Most recently, it was shown that the Mettl3-Mettl14 writer complex of this mark is required for the temporal control of cortic...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984442/ https://www.ncbi.nlm.nih.gov/pubmed/29855337 http://dx.doi.org/10.1186/s13059-018-1436-y |