Cargando…
Ythdf2-mediated m(6)A mRNA clearance modulates neural development in mice
BACKGROUND: N(6)-methyladenosine (m(6)A) modification in mRNAs was recently shown to be dynamically regulated, indicating a pivotal role in multiple developmental processes. Most recently, it was shown that the Mettl3-Mettl14 writer complex of this mark is required for the temporal control of cortic...
Autores principales: | Li, Miaomiao, Zhao, Xu, Wang, Wei, Shi, Hailing, Pan, Qingfei, Lu, Zhike, Perez, Sonia Peña, Suganthan, Rajikala, He, Chuan, Bjørås, Magnar, Klungland, Arne |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984442/ https://www.ncbi.nlm.nih.gov/pubmed/29855337 http://dx.doi.org/10.1186/s13059-018-1436-y |
Ejemplares similares
-
Histone Methylations Define Neural Stem/Progenitor Cell Subtypes in the Mouse Subventricular Zone
por: Zhang, Zhichao, et al.
Publicado: (2019) -
m(6)A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition
por: Zhao, Boxuan Simen, et al.
Publicado: (2017) -
PML regulates neuroprotective innate immunity and neuroblast commitment in a hypoxic–ischemic encephalopathy model
por: Palibrk, Vuk, et al.
Publicado: (2016) -
PML Regulates the Epidermal Differentiation Complex and Skin Morphogenesis during Mouse Embryogenesis
por: Połeć, Anna, et al.
Publicado: (2020) -
Parp3 promotes astrocytic differentiation through a tight regulation of Nox4-induced ROS and mTorc2 activation
por: Rodriguez-Vargas, José-Manuel, et al.
Publicado: (2020)