Dietary supplementation with ketoacids protects against CKD-induced oxidative damage and mitochondrial dysfunction in skeletal muscle of 5/6 nephrectomised rats

BACKGROUND: A low-protein diet supplemented with ketoacids (LPD + KA) maintains the nutritional status of patients with chronic kidney disease (CKD). Oxidative damage and mitochondrial dysfunction associated with the upregulation of p66SHC and FoxO3a have been shown to contribute to muscle atrophy....

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Dongtao, Wei, Lianbo, Yang, Yajun, Liu, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984473/
https://www.ncbi.nlm.nih.gov/pubmed/29855350
http://dx.doi.org/10.1186/s13395-018-0164-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984473/
https://www.ncbi.nlm.nih.gov/pubmed/29855350
http://dx.doi.org/10.1186/s13395-018-0164-z

Ejemplares similares