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Chaperone AMPylation modulates aggregation and toxicity of neurodegenerative disease-associated polypeptides
Proteostasis is critical to maintain organismal viability, a process counteracted by aging-dependent protein aggregation. Chaperones of the heat shock protein (HSP) family help control proteostasis by reducing the burden of unfolded proteins. They also oversee the formation of protein aggregates. He...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984528/ https://www.ncbi.nlm.nih.gov/pubmed/29760078 http://dx.doi.org/10.1073/pnas.1801989115 |