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Characterization of tumor heterogeneity by latent haplotypes: a sequential Monte Carlo approach
Tumor samples obtained from a single cancer patient spatially or temporally often consist of varying cell populations, each harboring distinct mutations that uniquely characterize its genome. Thus, in any given samples of a tumor having more than two haplotypes, defined as a scaffold of single nucle...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
PeerJ Inc.
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984585/ https://www.ncbi.nlm.nih.gov/pubmed/29868266 http://dx.doi.org/10.7717/peerj.4838 |