Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation

OBJECTIVE: Tumor necrosis factor-inducible gene 6 (TSG-6) has anti-inflammatory and chondroprotective effects in mouse models of inflammatory arthritis. Because cartilage damage and inflammation are also observed in osteoarthritis (OA), we determined the effect of viral overexpression of TSG-6 in ex...

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Detalles Bibliográficos
Autores principales: Broeren, Mathijs G.A., Di Ceglie, Irene, Bennink, Miranda B., van Lent, Peter L.E.M., van den Berg, Wim B., Koenders, Marije I., Blaney Davidson, Esmeralda N., van der Kraan, Peter M., van de Loo, Fons A.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984587/
https://www.ncbi.nlm.nih.gov/pubmed/29868252
http://dx.doi.org/10.7717/peerj.4771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984587/
https://www.ncbi.nlm.nih.gov/pubmed/29868252
http://dx.doi.org/10.7717/peerj.4771

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