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Application of enhanced electronegative multimodal chromatography as the primary capture step for immunoglobulin G purification

In recent studies, electronegative multimodal chromatography with Eshmuno HCX was demonstrated to be a highly promising recovery step for direct immunoglobulin G (IgG) capture from undiluted cell culture fluid. In this study, the binding properties of HCX to IgG at different pH/salt combinations wer...

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Detalles Bibliográficos
Autores principales: Wang, Yanli, Chen, Quan, Xian, Mo, Nian, Rui, Xu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984612/
https://www.ncbi.nlm.nih.gov/pubmed/29858705
http://dx.doi.org/10.1186/s13568-018-0622-3