Cargando…

Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter

Ten-eleven translocation (Tet) family-mediated DNA oxidation represents an epigenetic modification capable of converting 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC), which regulates various biological processes. However, it is unknown whether Tet family affects mesenchymal stem cells...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Ruili, Yu, Tingting, Kou, Xiaoxing, Gao, Xiang, Chen, Chider, Liu, Dawei, Zhou, Yanheng, Shi, Songtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984622/
https://www.ncbi.nlm.nih.gov/pubmed/29858571
http://dx.doi.org/10.1038/s41467-018-04464-6