Dynamic structural states of ClpB involved in its disaggregation function

The ATP-dependent bacterial protein disaggregation machine, ClpB belonging to the AAA+ superfamily, refolds toxic protein aggregates into the native state in cooperation with the cognate Hsp70 partner. The ring-shaped hexamers of ClpB unfold and thread its protein substrate through the central pore....

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Detalles Bibliográficos
Autores principales: Uchihashi, Takayuki, Watanabe, Yo-hei, Nakazaki, Yosuke, Yamasaki, Takashi, Watanabe, Hiroki, Maruno, Takahiro, Ishii, Kentaro, Uchiyama, Susumu, Song, Chihong, Murata, Kazuyoshi, Iino, Ryota, Ando, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984625/
https://www.ncbi.nlm.nih.gov/pubmed/29858573
http://dx.doi.org/10.1038/s41467-018-04587-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984625/
https://www.ncbi.nlm.nih.gov/pubmed/29858573
http://dx.doi.org/10.1038/s41467-018-04587-w

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