Recurrent rearrangements of FOS and FOSB define osteoblastoma

The transcription factor FOS has long been implicated in the pathogenesis of bone tumours, following the discovery that the viral homologue, v-fos, caused osteosarcoma in laboratory mice. However, mutations of FOS have not been found in human bone-forming tumours. Here, we report recurrent rearrange...

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Detalles Bibliográficos
Autores principales: Fittall, Matthew W., Mifsud, William, Pillay, Nischalan, Ye, Hongtao, Strobl, Anna-Christina, Verfaillie, Annelien, Demeulemeester, Jonas, Zhang, Lei, Berisha, Fitim, Tarabichi, Maxime, Young, Matthew D., Miranda, Elena, Tarpey, Patrick S., Tirabosco, Roberto, Amary, Fernanda, Grigoriadis, Agamemnon E., Stratton, Michael R., Van Loo, Peter, Antonescu, Cristina R., Campbell, Peter J., Flanagan, Adrienne M., Behjati, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984627/
https://www.ncbi.nlm.nih.gov/pubmed/29858576
http://dx.doi.org/10.1038/s41467-018-04530-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984627/
https://www.ncbi.nlm.nih.gov/pubmed/29858576
http://dx.doi.org/10.1038/s41467-018-04530-z

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